Being unable to use the Windows key after an update often happens if the files or drivers are damaged or not compatible. You should type sfc /scannow and DISM /Online /Cleanup-Image /RestoreHealth in Command Prompt, being an administrator. You should check the Group Policy Editor (gpedit.msc) to check if the Windows key is locked by any policy.

For more read -https://datarecovee.com/windows-key-not-working/